This report provides an extensive analysis of the Global In Vitro Toxicology Testing Market, including drivers, restraints, opportunities, trends, and forecasts for the period 2018-2024. In vitro toxicology involves the study of cells or tissues grown or maintained in precise laboratory conditions to assess the toxic properties of compounds. These testing methods allow the observation of toxicity at the cellular level without the complex physiological systemic effects often seen in living organisms.
In vitro methods are increasingly used and can be correlated with in vivo studies, aiding in understanding specific in vivo responses in various animal species. Industries such as pharmaceuticals, chemicals, food, cosmetics, medical devices, and diagnostics rely on in vitro toxicology testing to assess the safety (toxicity) and efficacy of drugs, chemicals, biochemicals, materials, and preparations. While most information about potential drug toxicity comes from animal models, there is a growing need for innovative in vitro models using human-based cell models for more predictive human health outcomes.
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The market for in vitro toxicology testing is driven by strong opposition to animal testing, increased costs associated with animal-based toxicity testing, and growing research and development (R&D) expenditure for early-stage toxicity testing. However, the lack of in vitro models and a reduced adoption rate pose limitations to market growth.
Market Analysis
The “Global In Vitro Toxicology Testing Market” is projected to experience a Compound Annual Growth Rate (CAGR) of 8.2% during the forecast period from 2018 to 2024. The global market analysis is based on three segments: toxicology endpoints, industry type, and regions.
Regional Analysis
The regions covered in this report include North America, Europe, Asia Pacific, and the Rest of the World (RoW). Europe holds the largest share in the global in vitro toxicology testing market, followed by North America. Increased investments by the European Commission in R&D to develop alternative methods to in vivo testing are driving demand in this region. Asia Pacific is expected to grow at a high CAGR during the forecast period, driven by the increasing number of contract research organizations offering testing services, advancements in healthcare infrastructure, growing investments in the biopharmaceutical sector, and improved economic conditions in the region.
Toxicology Endpoints Analysis
The in vitro toxicology testing market, segmented by toxicology endpoints, includes systemic toxicity, cytotoxicity testing, genotoxicity testing, ocular toxicity, organ toxicity, dermal toxicity, neurotoxicity, and others. Systemic toxicity accounted for the highest market share in 2017 due to the availability of a wide range of sub-studies ensuring a comprehensive analysis of toxicity and safety margins of testing compounds.
Industry Type Analysis
The in vitro toxicology testing market, categorized by industry type, includes pharmaceutical and biopharmaceutical, cosmetics, chemical, diagnostics, and food industries. The pharmaceutical and biopharmaceutical industry held a significant market share in 2017, while the cosmetics industry is expected to have a higher percentage during the forecast period. Support from regulatory authorities to use in vitro and in silico methods instead of animal testing to assess toxicity is driving the growth of the cosmetic industry.
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Key Players
Major players in the market include Laboratory Corporation of America Holdings, Charles River Laboratories, Inc., Bio-Rad Laboratories, GE Healthcare, Thermo Fisher Scientific, Eurofins Scientific, SGS SA, BioIVT, Agilent Technologies, Inc., Abbott Laboratories, Gentronix Limited, Promega Corporation, MB Research Laboratories, Evotec AG (Cyprotex plc), Catalent, Inc., and Qiagen N.V., among others.
Competitive Analysis
Companies are increasingly collaborating on in vitro testing of compounds. For example, in December 2016, Evotec and Celgene entered into a drug discovery collaboration for neurodegenerative diseases, utilizing Evotec’s induced pluripotent stem cell (iPSC) platform. In June 2017, Censo Biotechnologies Ltd. collaborated with Evotec AG to provide patient-derived induced pluripotent stem cells to support Evotec’s drug discovery iPSC platform. Additionally, companies are launching new products for in vitro testing. In January 2018, STEMCELL Technologies Inc. introduced two product lines for organoid research, enabling scientists to create powerful models for studying human diseases in the laboratory.
Benefits
This report offers comprehensive insights into the services provided by in vitro toxicology testing companies across various therapeutic verticals and regions. Key stakeholders can gain knowledge about major trends, drivers, investments, and initiatives by industry players and governments. Additionally, the report highlights significant challenges that may impact market growth and identifies key business opportunities for stakeholders seeking to expand their presence and revenue in specific verticals. It serves as a valuable resource for informed decision-making before investing in or expanding business operations within this market.
Key Stakeholders
- Healthcare providers
- Pharmaceutical companies
- Regulatory authorities
- Research institutions
- Distributors and suppliers
- Patients and caregivers
- Investors and venture capitalists
Market Dynamics:
Surging air traffic:
- As the global aviation industry continues to expand, there is a corresponding increase in market demand.
Heightened emphasis on safety and reliability:
- The aerospace and defense sector places significant importance on ensuring safety and reliability, which drives the need for top-notch market offerings.
Growing commitment to environmental sustainability:
- The aerospace and defense industry is increasingly dedicated to reducing its carbon footprint, resulting in the adoption of sustainable aviation fuels.
Escalating globalization:
- The growth of international trade and travel propels the demand for market solutions.
Increasing desire for private air transportation:
- The rising number of affluent individuals and their preference for exclusive air travel are generating fresh opportunities in the market.
Expanding utilization of digital fuel management systems:
- The integration of digital fuel management systems facilitates efficient fuel consumption and reduces associated costs.
Advancements in fuel cell technology:
- Ongoing developments in fuel cell technology unlock new possibilities for the production of sustainable market alternatives.
Mounting demand for air cargo transportation:
- The flourishing e-commerce sector fuels an increasing need for air cargo transportation, thereby driving the demand for market offerings.
Rising defense budgets:
- Governments worldwide are augmenting their defense spending, leading to heightened market demand.
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