“Final Report will add the analysis of the impact of COVID-19 on industry.”
Report Ocean has recently published a comprehensive study on the Antibody Drug Conjugates (ADC) Market, covering the prediction period of 2023-2031. Throughout the years, this report has diligently examined the industry, taking into account various factors such as macroeconomic parameters, consumer buying patterns, microeconomic parameters, GDP growth rate, inflation rate, and market demand-supply scenarios.
market players, such as [F. Hoffmann-La Roche AG, Seagen, Inc. (Seattle Genetics Inc.), Daiichi Sankyo Company Ltd., AstraZeneca plc, Pfizer Inc., GlaxoSmithKline plc, Gilead Sciences, Inc., Takeda Pharmaceutical Company Limited, Genentech Inc., Astellas Pharma Inc
Russia-Ukraine War on Market
The market is anticipated to suffer because of the Russia-Ukraine War. The demand for the market has decreased as a result of the political unrest and economic unrest in the area. The war had a detrimental impact on global economic activity, adding to inflationary pressures globally and hindering the post-pandemic recovery, even if it was not the primary cause of the slower-than-anticipated economic growth in 2022 and revised estimates for 2023.
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The healthcare sector is vital to both national economies and people all across the world. One of the industries with the fastest growth rates is this one. There is a correlation between income levels and healthcare spending across nations because healthcare spending accounts for more than 10% of the GDP of the majority of developed countries. According to the Centers for Medicare and Medicaid Services, US healthcare spending increased by 4.6% in 2019 to reach US$ 3.8 trillion, or US$ 11,582 per person and represented 17.7% of GDP. Additionally, households paid for 28.4% of all health expenditures, followed by the federal government for 29.0%. 16.1% of all healthcare costs were paid for by state and municipal governments, while 7.5% came from other private sources.
ADC Market Set for Promising Growth Forecast to Reach USD 14.4 Billion by 2027
The global ADC market is growing at an impressive CAGR. The growing advancement in linker technologies, coupled with extensive research & development in the medical field, is driving the growth of the global ADC market
A recent study by the strategic consulting and market research firm:Report Ocean revealed that the Global ADC market was worth USD 4,053.7 million in 2021. The market is further anticipated to reach USD 14,484.2 million in 2027 with a significant CAGR of 25.2% during the forecast period, i.e., 2022-2027. The increasing incidence of cancer cases across the globe is propelling the growth of the global ADC (antibody-drug conjugate) market. For instance, according to the American Cancer Society, the estimated number of new cancer cases and deaths recorded for 2021 were around 1.9 million and 608,570, respectively, across the United States.
In the coming years, ADC drug development will be facilitated by the increasing number of governmental healthcare programs and grants awarded to certain research organizations. Such factors, coupled with an increasing number of FDA approvals positively impact the growth of the global ADC Market.
Rising Number of Trials Pertaining to ADC Drugs Creating Lucrative Opportunities for Market Growth
The American Cancer Society estimates 36 ongoing trials with more than 20 ADCs combined with immuno-oncology (IO) therapies. With an estimated 100+ clinical trials going on around the world in 2019, there has been a growing inclination toward the production of ADCs in the market. Moreover, with the increasing number of approvals from the Food & Drug Administration (FDA), the ADC drug class has started to become an emerging drug in the market. However, some strict regulations have rendered over 20% of the ADC trials null and void. The FDA has found that more than 12 of the ADC drugs are in Phase II or Phase III (final stage) clinical trials, suggesting a growing number of approvals that the FDA may deliver in the coming years, thereby providing more opportunities for the growth of the market as these drugs could start to become accessible by low and middle-income countries that have long been eluded from the ADC drugs owing to their skyrocketing prices.
Downstream Processing & Technological Issues with ADC Anticipated to Impede Market Growth
Companies in the antibody-drug conjugate market report that the downstream processing process is a significant challenge impeding their growth. The production capabilities for suitable chemical linkers for connecting monoclonal antibodies and cytotoxic drugs are the biggest challenge across the downstream process for manufacturing and developing cost-effective ADC and are expected to impede the market growth.
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Impact of COVID-19 on the Global ADC Market
The COVID-19 pandemic has had a mixed impact on the global ADC market. The ADC has proven beneficial in treating cancer. According to the American Cancer Society, an estimated 1.8 million newer cancer cases and almost 606,500 cancer deaths were recorded in 2020. The number of cases recorded in 2020 were higher than the number of cases in 2019, which were 1.7 million. Thus, the growing incidence of cancer led to the growing demand for ADC during the pandemic. However, due to the lockdown and supply chain disruptions, factory operations were reduced, which resulted in reduced clinical studies and unavailability of important raw materials, monoclonal antibodies (mAbs), linkers, and technology involved in the production of ADCs. All these factors have negatively impacted the growth of the global antibody-drug conjugate market.
Cleavable Type Segment Accounted for Major Highest Market Share in the Growth of Global ADC Market
Based on types, the global ADC market is segmented into cleavable linkers and non-cleavable linkers. The cleavable linkers segment accounted for the largest market share in 2021. The rise in approval rate and pipeline molecules, coupled with the ongoing trial of cleavable linkers, are the key factors driving the segments growth. For instance, in September 2021, Japan’s Ministry of Health, Labor, and Welfare (MHLW) announced that they were issuing a license for PADCEV (enfortumab vedotin), as it has been profoundly found to tackle unresectable urothelial carcinoma, which has augmented anti-cancer chemotherapy capabilities, according to the research conducted by Seagen Inc. and Astellas Pharma Inc. The ADC approved by the Ministry happens to be a cleavable linker ADC used for treating urothelial cancer.
North America Dominates the Global ADC Market
Based on regions, the global ADC market is segmented into North America, Europe, the Asia-Pacific, Latin America, and the Middle East & Africa. The North America region held the largest market share in 2021. On the other hand, the Asia-Pacific region is expected to hold the largest CAGR during the forecast period. The increase in cancer cases in Asia-Pacific can be attributed to a variety of causes, including unhealthy lifestyles influenced by Western culture, the increase in alcohol and tobacco consumption, and the rise in pollution in South and Southeast Asia. Another factor contributing to the growth of cancer rates include the growing geriatric population.
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Market Segment:
By Type(Cleavable Linker And Non-Cleavable Linker)
By Application(Blood Cancer (Leukemia, Multiple Myeloma, Lymphoma, Breast Cancer, Urothelial Cancer & Bladder Cancer And Others)
By End Users(Research Institutes, Biotechnology Companies, Hospitals, And Clinics)
By Region (North America, Europe, The Asia-Pacific (APAC), Latin America (LATAM), The Middle-East & Africa (MEA))
Table of Content:
- Report Overview
- Global Growth Trends
- Competition Landscape by Key Players
- Data Segments
- North America Market Analysis
- Europe Market Analysis
- Asia-Pacific Market Analysis
- Latin America Market Analysis
- Middle East & Africa Market Analysis
- Key Players Profiles Market Analysis
- Analysts Viewpoints/Conclusions
- Appendix
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